Anti-REN Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K002855P-50ul	solarbio	50ul	960.00元
K002855P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-REN Polyclonal Antibody
别名	HNFJ2
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:100-200.
交叉反应	Human Mouse
蛋白分子量	45kDa
Gene ID	5972
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human REN
性状	液体
Public Immunogen Range	Recombinant protein of human REN
Subcellular Locations	Membrane Secreted
Swiss Prot	P00797
克隆类型	Polyclonal Antibody
背景资料	Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia.